Formation of Actin Filaments and Focal Adhesion within Fibrous Matrices

Deep learning reveals how cells pull, buckle, and navigate tissue-like environments

A Padhi, A Daw, A Agashe, M Sawhney, MM Talukder, A Agashe, M Mohammad Hossein Pour, M Jafari, GM Genin, F Alisafaei*, S Kale*, A Karpatne*, AS Nain*

Proceedings of the National Academy of Sciences (PNAS), 2025