top of page

Control

Disruption of Actin

Disruption of Microtubules

The balance between actomyosin contractility and microtubule polymerization regulates hierarchical protrusions that govern efficient fibroblast–collagen interactions

D Shakiba, F Alisafaei, A Savadipour, RA Rowe, Z Liu, KM Pryse, VB Shenoy, EL Elson, GM Genin

ACS Nano, 2020

Read Here

Tension anisotropy drives fibroblast phenotypic transition by self-reinforcing cell–extracellular matrix mechanical feedback

F Alisafaei, D Shakiba, Y Hong, G Ramahdita, Y Huang, LE Iannucci, MD Davidson, M Jafari, J Qian, C Qu, D Ju, DR Flory, Y-Y Huang, P Gupta, S Jiang, A Mujahid, S Singamaneni, KM Pryse, P-HG Chao, JA Burdick, SP Lake, EL Elson, N Huebsch, VB Shenoy, GM Genin

Nature Materials, 2025

Read Here

bottom of page